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SkinCeuticals

SkinCeuticals P-TIOX Anti-Wrinkle Cream (1.6 oz.)

SkinCeuticals P-TIOX Anti-Wrinkle Cream (1.6 oz.)

Wrinkle-Smoothing. Glass-Skin.

P-TIOX Cream is an advanced wrinkle and texture-correcting moisturizer that smooths deep lines, minimizes pores, and improves skin radiance. Powered by 10% Myrixin™, 2% tripeptide technology, niacinamide, LHA, and Tetrapeptide, it delivers lightweight hydration while enhancing skin clarity and smoothness for a radiant, glass-skin glow.

Benefits at a glance:

  • Visibly reduces deep set wrinkles + pores that neurotoxins alone do not treat*
  • Up to -33% visible wrinkles, -30% pore size
  • Boosts hydration by up to +94% in just 1 hour
  • Physician tested to complement neurotoxin injections
  • Suitable for all skin types and tones, even sensitive skin
  • Smooths skin texture with patent-pending Myrixin™ and advanced peptides
  • Achieves glass skin appearance when paired with P-TIOX serum
$127.50 USD
$150.00 USD $127.50 USD
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How to Use

Prep + Dispense
Twice daily, after applying a corrective serum, dispense a small amount into clean hands.

Apply + Complete
Gently press cream evenly into skin on face, neck and around the eyes. Follow with a SkinCeuticals sunscreen.

Shipping & Returns

We offer standard shipping on all orders, with delivery estimated between 5–7 business days. You’ll receive a tracking link as soon as your order ships.

We accept returns on unopened items within 14 days of delivery. To initiate a return, please contact our support team with your order details.

Please note: For health and safety reasons, we cannot accept returns on opened or used products.

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Key Ingredients

  • Dipeptide Diaminobutyroyl

    Is an anti-aging peptide that helps reduce the appearance of fine lines and expression wrinkles by relaxing facial muscle contractions.

  • Niacinamide (Vitamin B3)

    Discover the benefits of niacinamide (vitamin B3), an effective antioxidant that offers powerful environmental protection while being gentle enough for daily use or sensitive skin types.

  • Patented Micro-Peptide + Myrixin™ Technology for Skin Clarity

    Its patent-pending of peptide technology and Myrixin™, a proprietary flavonoid-rich complex inspired by neurotoxin-like effects, targets deep-set wrinkles, and pore dilation with precision.
View All Ingredients
AQUA / WATER / EAU ● BUTYLENE GLYCOL ● NIACINAMIDE ● GLYCERIN ● DICAPRYLYL CARBONATE ● PENTYLENE GLYCOL ● CETEARYL ALCOHOL ● 1,2-HEXANEDIOL ● ISODODECANE ● C14-22 ALCOHOLS ● CAPRYLIC/CAPRIC TRIGLYCERIDE ● VINYL DIMETHICONE ● MACADAMIA INTEGRIFOLIA SEED OIL ● GLYCERYL STEARATE SE ● C12-20 ALKYL GLUCOSIDE ● NYMPHAEA ALBA FLOWER EXTRACT ● ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER ● BUTYROSPERMUM PARKII BUTTER / SHEA BUTTER ● C12-16 ALCOHOLS ● TROMETHAMINE ● PSIDIUM GUAJAVA FRUIT EXTRACT ● CAMELLIA SINENSIS LEAF EXTRACT ● ALLIUM SATIVUM BULB EXTRACT / GARLIC BULB EXTRACT ● ZINC PCA ● CAPRYLOYL SALICYLIC ACID ● PSIDIUM GUAJAVA LEAF EXTRACT ● LUFFA CYLINDRICA FRUIT EXTRACT ● HYDROGENATED LECITHIN ● PALMITIC ACID ● CETYL PALMITATE ● ETHYLHEXYLGLYCERIN ● ADENOSINE ● SORBITAN STEARATE ● POLYSORBATE 80 ● TOCOPHEROL ● CERAMIDE NP ● DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE ● SODIUM BENZOATE ● CITRIC ACID ● PALMITOYL TETRAPEPTIDE-10

Want to know more about SkinCeuticals P-TIOX Anti-Wrinkle Cream (1.6 oz.)?

Frequently Asked Questions

How does P-TIOX Cream work?

P-TIOX Cream uses a patented combination of proprietary Myrixin™ and tripeptide technologies to visibly reduce deep-set wrinkles, refine texture, and help minimize the appearance of enlarged pores. Myrixin™ helps modulate oil activity, while the tripeptide supports structural firmness and surface smoothness.

This protective gel cream contains water-bursting micro-droplets that melt into the skin for rapid absorption, delivering instant smoothing and visible texture correction.

How long does it take for P-TIOX Cream to work?

Visible improvements, such as reduced pore visibility, can be seen in as little as one month. Continued daily use helps improve the appearance of deep-set wrinkles and refine overall texture. For optimal results, P-TIOX Cream should be used consistently and paired with P-TIOX serum to support the full glass skin routine.

Can you use P-TIOX Cream with retinol?

Yes, P-TIOX Cream can be used in a routine that includes retinol. During your nighttime routine, apply P-TIOX cream after the retinol. As with any skincare combination, monitor skin tolerance and consult your skincare professional if needed.

What are the key differences between P-TIOX Serum and P-TIOX Cream?

P-TIOX Serum is a concentrated treatment that targets visible expression lines and supports skin smoothness resulting in glass skin radiance with a fluid, transparent formula. P-TIOX Cream complements the serum by addressing pores, deep-set wrinkles, and surface texture while delivering hydration in a fresh cream texture that leaves a non-greasy finish. Used together, they create a complete routine for achieving a glass skin effect.

What is glass skin and how can I achieve it?

Glass skin refers to a complexion that appears visibly smooth, luminous, and poreless. Achieving this look involves skincare that targets texture, clarity, and hydration. P-TIOX Cream helps refine texture and reduce shine, and when paired with P-TIOX Serum, contributes to achieving a visibly radiant, even-toned complexion.

Is P-TIOX Cream safe to use after neurotoxin injections?

Is P-TIOX Cream safe to use after neurotoxin injections?
Yes. P-TIOX Cream is designed to complement neurotoxin injections by helping prolong visible results and supporting smoother skin texture. It is suitable for post-procedure use, though you should always consult your provider for personalized post-treatment care.